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Condition guideCancer & palliative

Chemotherapy-induced nausea & vomiting

Strong evidence that THC-based medicines reduce refractory chemotherapy nausea and vomiting, used as a second- or third-line add-on.

Strong evidence

Last reviewed 15 June 2026 · Education, not medical advice

Supported by high-quality randomised controlled trials for specific situations.

Can medicinal cannabis help with chemo nausea (cinv) in NZ?

Strong evidence for chemo nausea (cinv). Strong evidence that THC-based medicines reduce refractory chemotherapy nausea and vomiting, used as a second- or third-line add-on.There is no fixed list of qualifying conditions in NZ — whether it's appropriate for you is a clinical judgement for a registered doctor. This is education, not a treatment recommendation.

What the evidence says

A Cochrane review found that, versus placebo, cannabinoids tripled the chance of complete absence of nausea and vomiting (RR 2.9, 95% CI 1.8–4.7), and patients preferred them (RR 3.3). The US National Academies graded this 'conclusive'. The important caveat: the pivotal trials predate modern 5-HT3 and NK1 antiemetics, so the advantage over today's standard regimens is uncertain. It is used as an add-on after standard antiemetics, not first-line.

Cannabinoids studied

  • THC

Key cautions

  • Dysphoria, dizziness, feeling 'high', postural hypotension and faster heart rate.
  • Adverse effects can force some patients to stop.
  • Caution with CNS depressants and in psychiatric vulnerability.

Sources

Peer-reviewed reviews, trial data and official guidance. We never fabricate figures.

What to do next

If you think medicinal cannabis might help with chemo nausea (cinv), the next step is a conversation with a registered New Zealand doctor, who can weigh your individual situation. Start with your own GP or a clinic that focuses on cannabis medicine. Our step-by-step pathway walks through the whole process, and our self-check can help you prepare.

This is general information, not medical advice. Only a registered New Zealand doctor can decide whether medicinal cannabis is right for you.

Reviewed for accuracy by the mc.nz editorial team against the cited sources. Last reviewed 15 June 2026.